Порозов Юрий Борисович


кандидат медицинских наук, доцент
yuri_porozov@itmo.ru

Профиль:
02.00.04 - Физическая химия

Область интересов:
Моделирование селективных ингибиторов кальциневрина in silico и их верификация
Рабочий язык:
Английский

Публикации руководителя
Выходные данные Год Индексирование в БД
Сенина А.С., Пац К.М., Москвин А.В., Порозов Ю.Б. Компьютерное моделирование взаимодействия гидрогалогенидов амидразонов с белками-мишенями // Фармация -2020. - Т. 69. - № 8. - С. 50-56 2020 ВАК, РИНЦ
Solovev Y.V., Ostroverkhova D.S., Tamazian G.S., Domnin A.V., Anashkina A.A., Petrushanko I.Y., Stepanov E.O., Porozov Y.B. Na/K-ATPase Glutathionylation: in silico Modeling of Reaction Mechanisms//Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 2020, Vol. 12304 LNBI, pp. 372-380 2020 Scopus, Web of Science
Tinkov O., Polishchuk P., Grigorev V., Porozov Y. The Cross-Interpretation of QSAR Toxicological Models//Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 2020, Vol. 12304 LNBI, pp. 262-273 2020 Scopus, Web of Science
Delfino F., Porozov Y., Stepanov E., Tamazian G., Tozzini V. Evolutionary Switches Structural Transitions via Coarse-Grained Models//Journal of Computational Biology, 2020, Vol. 27, No. 2, pp. 189–199 2020 Scopus, Web of Science
Moldogazieva N.Т., Ostroverkhova D.S., Kuzmich N.N., Kadochnikov V.V., Terentiev A.A., Porozov Y.B. Elucidating Binding Sites and Affinities of ER Alpha Agonists and Antagonists to Human Alpha-Fetoprotein by In Silico Modeling and Point Mutagenesis//International Journal of Molecular Sciences, 2020, Vol. 21, No. 3, pp. 893 2020 Scopus, Web of Science
Ostroverkhova D.S., Hu J., Tarasov V.V., Melnikova T.I., Porozov Y.B., Mutig K. Calcium-Sensing Receptor and Regulation of WNK Kinases in the Kidney//Cells, 2020, Vol. 9, No. 7, pp. 1644 2020 Scopus, Web of Science
Пац К.М., Порозов Ю.Б. CIS-белок - новая мишень в иммунотерапии рака, или Следствие ведут биоинформатики // Природа -2019. - № 2(1242). - С. 49-54 2019 ВАК, РИНЦ
Popova E.A., Protas A., Mukhametshina A., Ovsepyan G., Suezov R., Eremin A., Stepchenkova E., Tarakhovskaya E., Fonin A., Starova G.L., Mikolaichuk O.V., Porozov Y.B., Gureev M.A., Trifonov R.E. Synthesis, biological evaluation and molecular docking studies on the DNA and BSA binding interactions of palladium(II) and platinum(II) complexes featuring amides of tetrazol-1-yl- and tetrazol-5-ylacetic acids//Polyhedron, 2019, Vol. 158, pp. 36-46 2019 Scopus, Web of Science
Terekhov R.P., Selivanova I.A., Tyukavkina N.A., Shylov G.A., Utenishev A.N., Porozov Y.B. Taxifolin tubes: crystal engineering and characteristics//Acta Crystallographica Section B: Structural Science, Crystal Engineering and Materials, 2019, Vol. 75, No. 2, pp. 175-182 2019 Scopus, Web of Science
Терехов Р.П., Селиванова И.А., Жевлаков А.К., Порозов Ю.Б., Дзубан А.В. Анализ физических модификаций дигидрокверцетина in vitro и in silico [Analysis of dihydroquercetin physical modification via in vitro and in silico methods] // Биомедицинская химия [Biomeditsinskaya Khimiya] -2019. - Т. 65. - № 2. - С. 152-158 2019 Scopus, ВАК, РИНЦ
Fedorov B.A., Smirnov A.V., Yaroshenko V.V., Porozov Y.B. SASCUBE: An Updated Method of Cubes for Calculation of the Intensity of X-Ray Scattering by Biopolymers in Solution//Biophysics, 2019, Vol. 64, No. 1, pp. 38-48 2019 Scopus
Федоров Б.А., Смирнов А.В., Ярошенко В.В., Порозов Ю.Б. Sascube – обновленный метод кубиков для pаcчета интенcивноcти pентгеновcкого pаccеяния биополимеpов в pаcтвоpе // Биофизика [Biofizika] -2019. - Т. 64. - № 1. - С. 48-60 2019 ВАК, РИНЦ
Delfino F., Porozov Y.B., Stepanov E., Tamazian G., Tozzini V. Structural Transition States Explored With Minimalist Coarse Grained Models: Applications to Calmodulin//Frontiers in molecular bioscience, 2019, Vol. 6, pp. 104 2019 Scopus, Web of Science
Moldogazieva N., Mokhosoev I., Mel'Nikova T., Porozov Y.B., Terentiev A. Oxidative stress and advanced lipoxidation and glycation end products (ALEs and AGEs) in aging and age-related diseases//Oxidative Medicine and Cellular Longevity, 2019, Vol. 2019, pp. 3085756 2019 Scopus, Web of Science
Tuaeva N., Falzone L., Porozov Y.B., Nosyrev A.E., Trukhan V.M., Kovatsi L., Spandidos D.A., Drakoulis N., Kalogeraki A., Mamoulakis C., Tzanakakis G., Libra M., Tsatsakis A. Translational Application of Circulating DNA in Oncology: Review of the Last Decades Achievements//Cells, 2019, Vol. 8, No. 10, pp. 1251 2019 Scopus, Web of Science
Kashkin V.A., Shekunova E.V., Titov M.I., Eliseev I.I., Gureev M.A., Porozov Y.B., Makarova M.N., Makarov V.G. A new tridecapeptide with an octaarginine vector has analgesic therapeutic potential and prevents morphine-induced tolerance//Peptides, 2018, Vol. 99, pp. 61-69 2018 Scopus, Web of Science
Ilatovskaia D.B., Porozov Y.B., Demchenko P.S., Meglinski I.V., Khodzitsky M.K. The impact of optical radiation of femtosecond duration on human glial cells//Proceedings of SPIE, 2018, Vol. 10820, pp. 108203G 2018 Scopus, Web of Science
Kirienko A.N., Porozov Y.B., Malkov N.V., Akhtemova G.A., Le Signor C., Thompson R., Saffray C., Dalmais M., Bendahmane A., Tikhonovich I.A., Dolgikh E.A. Role of a receptor-like kinase K1 in pea Rhizobium symbiosis development//Planta, 2018, Vol. 248, No. 5, pp. 1101–1120 2018 Scopus, Web of Science
Igolkina A., Porozov Y.B., Chizhevskaya E.P., Andronov E.E. Structural insight into the role of mutual polymorphism and conservatism in the contact zone of the NFR5–K1 heterodimer with the Nod factor//Frontiers in Plant Science, 2018, Vol. 9, pp. 344 2018 Scopus, Web of Science
Protas A., Popova E.A., Mikolaichuk O.V., Porozov Y.B., Mehtiev A.R., Ott I., Alekseev G.V., Kasyanenko N.A., Trifonov R.E. Synthesis, DNA and BSA binding of Pd(II) and Pt(II) complexes featuring tetrazolylacetic acids and their esters//Inorganica Chimica Acta, 2018, Vol. 473, pp. 133-144 2018 Scopus, Web of Science
Kuzmich N.N., Sivak K.V., Chubarev V.N., Porozov Y.B., Savateeva-Lyubimova T.N., Peri F. TLR4 signaling pathway modulators as potential therapeutics in inflammation and sepsis//Vaccines, 2017, Vol. 5, No. 4, pp. 34 2017 Scopus, Web of Science
Lutsenko E., Knyazev S.N., Porozov Y.B. A New Approach for Modeling of Conformational Changes of Multi Chain Proteins//Procedia Computer Science, 2016, Vol. 101, pp. 58-67 2016 Scopus, Web of Science
Knyazev S.N., Kalyakin V.Y., Deryabin I.N., Fedorov B.A., Smirnov A.V., Stepanov E.O., Porozov Y.B. Prediction of protein conformational mobility with validation using small-angle X-ray scattering//Biophysics, 2015, Vol. 60, No. 6, pp. 886-892 2015 Scopus
Князев С.Н., Калякин В.Ю., Дерябин И.Н., Федоров Б.А., Смирнов А.В., Степанов Е.О., Порозов Ю.Б. Предсказание конформационной подвижности белков и оценка ее достоверности с помощью малоуглового рентгеновского рассеяния [Prediction of Protein Conformational Mobility and Evaluation of Its Reliability Using Small-Angle X-ray Scattering] // Биофизика [Biofizika] -2015. - Т. 60. - № 6. - С. 1069–1076 2015 Scopus, ВАК, РИНЦ
Tamazian G.S., Ho Chang J., Knyazev S., Stepanov E., Kim K., Porozov Y.B. Modeling conformational redox-switch modulation of human succinic semialdehyde dehydrogenase//Proteins: Structure, Function and Bioinformatics, 2015, Vol. 83, No. 12, pp. 2217-2229 2015 Scopus, Web of Science
Knyazev S., Tarakanov S., Kuznetsov V., Porozov Y., Koucheryavy Y.A., Stepanov E. Coarse-grained model of protein interaction for bio-inspired nano-communication//Ultra Modern Telecommunications and Control Systems and Workshops (ICUMT), 2014 6th International Congress on, 2014, pp. 260-262 2014 Scopus, Web of Science
Buzdalov M., Knyazev S., Porozov Y. Protein Conformation Motion Modeling using sep-CMA-ES//Proceedings - 2014 13th International Conference on Machine Learning and Applications, ICMLA 2014, 2014, pp. 35-40 2014 Scopus, Web of Science
Кошевой А.А., Степанов Е.О., Порозов Ю.Б. Метод предсказания и оптимизации конформационной подвижности белков путем решения транспортной задачи переноса массы [Method of prediction and optimization of conformational motion of proteins based on mass transportation principle] // Биофизика [Biofizika] -2014. - Т. 59. - № 1. - С. 37-44 2014 Scopus, ВАК, РИНЦ
Pershina E.V., Dolnik A.S., Tamazyan G.S., Vyatkina K.V., Porozov Y.B., Pinaev A.G., Karimov S.O., Provorov N.A., Andronov E.E. The Evolutionary Space Model to be Used for the Metagenomic Analysis of Molecular and Adaptive Evolution in the Bacterial Communities//Evolutionary Biology: Genome Evolution, Speciation, Coevolution and Origin of Life, 2014, pp. 339-355 2014 Scopus
Koshevoy A.A., Stepanov E.O., Porozov Y.B. Method of prediction and optimization of conformational motion of proteins based on mass transportation principle//Biophysics, 2014, Vol. 59, No. 1, pp. 28-34 2014 Scopus
Никитин Т.А., Порозов Ю.Б. Программная система и информационный банк метаданных третичных структур белков // Научно-технический вестник информационных технологий, механики и оптики [Scientific and Technical Journal of Information Technologies, Mechanics and Optics] -2013. - № 1(83). - С. 94-99 2013 ВАК, РИНЦ
Иголкина А.А., Андронов Е.Е., Порозов Ю.Б. Метод поиска субстратспецифичных областей ферментов класса целлюлаз на основании их первичной и третичной структур [Method of Search for Substrate Specificity Regions in Cellulase Class Enzymes Based on their Primary and Tertiary Structures] // Математическая биология и биоинформатика [Mathematical Biology and Bioinformatics] -2013. - Т. 8. - № 2. - С. 407-418 2013 Scopus, ВАК, РИНЦ
Спельников Д.М., Князев С.Н., Балахонцева М.А., Буздалов М.В., Порозов Ю.Б., Маслов В.Г., Бухановский А.В. Высокопроизводительный программный комплекс моделирования конформационно-зависимых свойств белков в задачах рационального дизайна лекарственных препаратов // Динамика сложных систем - XXI век -2013. - Т. 7. - № 3. - С. 12-16 2013 ВАК, РИНЦ
Tikhvinskiy D.A., Porozov Y.B. Bioinformatics and tools for computer analysis and visualization of macromolecules//Russian Open Medical Journal, 2013, Vol. 2, No. 1, pp. 0101 2013 РИНЦ
Porozov Y.B., Muntyan A.N., Chizhevskaya E.P., Simarov B.V., Andronov E.E. Conjugate Symbiotic Populations Part II: Analysis of nfr5 Receptor Gene Polymorphisms Using Molecular Docking//Russian Journal of Genetics: Applied Research, 2013, Vol. 3, No. 2, pp. 146-151 2013 Scopus
Спельников Д.М., Порозов Ю.Б., Маслов В.Г., Бухановский А.В. Моделирование конформационно-зависимых свойств белков для рационального дизайна лекарственных препаратов в среде облачных вычислений CLAVIRE // Научно-технический вестник информационных технологий, механики и оптики [Scientific and Technical Journal of Information Technologies, Mechanics and Optics] -2013. - № 5(87). - С. 175-176 2013 ВАК, РИНЦ
Igolkina A.A., Andronov E.E., Porozov Y.B. Method of Search for Substrate Specificity Regions in Cellulase Class Enzymes Based on their Primary and Tertiary Structures//Mathematical Biology and Bioinformatics, 2013, Vol. 8, No. 2, pp.  t1-t11 2013 Scopus
Дольник А.С., Тамазян Г.С., Першина Е.В., Вяткина К.В., Порозов Ю.Б., Пинаев А.Г., Андронов Е.Е. Концепция универсальной таксономической системы бактерий: эволюционное пространство гена 16S-рРНК v. 1.0 // Сельскохозяйственная биология [Sel'skokhozyaistvennaya Biologiya] -2012. - Т. 47. - № 5. - С. 112-120 2012 ВАК, РИНЦ